Braintown

Braintown is a software tool that automatically identifies dendritic spines in live, fluorescent tissue, utilizing a machine learning approach to minimize user input. The software cleans fluorescent images and trains a neural network using features based on the relative shape of the spine perimeter and its corresponding dendritic backbone. Braintown has over 90% accuracy in spine detection and is bundled with user-friendly, open-source, MATLAB-based software for spine analysis, making it a rapid and flexible tool for studying synaptic plasticity.

Topic

Machine learning;Cell biology;Biological imaging

Detail

  • Operation: Image analysis

  • Software interface: Graphical user interface

  • Language: MATLAB

  • License: -

  • Cost: Free

  • Version name: -

  • Credit: -

  • Input: -

  • Output: -

  • Contact: Michael.Smirnov@mpfi.org

  • Collection: -

  • Maturity: -

Publications

  • An open-source tool for analysis and automatic identification of dendritic spines using machine learning.
  • Smirnov MS, et al. An open-source tool for analysis and automatic identification of dendritic spines using machine learning. An open-source tool for analysis and automatic identification of dendritic spines using machine learning. 2018; 13:e0199589. doi: 10.1371/journal.pone.0199589
  • https://doi.org/10.1371/journal.pone.0199589
  • PMID: 29975722
  • PMC: PMC6033424

Download and documentation

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