C-State

BACKGROUND: Comparative epigenomic analysis across multiple genes presents a
bottleneck for bench biologists working with NGS data. Despite the development of
standardized peak analysis algorithms, the identification of novel epigenetic
patterns and their visualization across gene subsets remains a challenge.
RESULTS: We developed a fast and interactive web app, C-State (Chromatin-State),
to query and plot chromatin landscapes across multiple loci and cell types.
C-State has an interactive, JavaScript-based graphical user interface and runs
locally in modern web browsers that are pre-installed on all computers, thus
eliminating the need for cumbersome data transfer, pre-processing and prior
programming knowledge. CONCLUSIONS: C-State is unique in its ability to extract
and analyze multi-gene epigenetic information. It allows for powerful GUI-based
pattern searching and visualization. We include a case study to demonstrate its
potential for identifying user-defined epigenetic trends in context of gene
expression profiles.

C-State: an interactive web app for simultaneous multi-gene visualization and comparative epigenetic pattern search.

C-state (Chromatin-State) is a web-based tool to visualize the epigenetic landscape of DNA data.

C-state

Topic

Detail

Publications

Download and documentation