CLD

CLD (CRISPR library designer) is a software package to design single guide RNA (sgRNA) libraries using annotated genome data and modified CRISPR enzymes.

Topic

RNA;Genetics;Gene structure;Data submission, annotation and curation

Detail

  • Operation: Query and retrieval

  • Software interface: Command-line user interface

  • Language: C++, Perl, C

  • License: GNU General Public License v2

  • Cost: Free

  • Version name: 1.4.4

  • Credit: ERC Advanced Grant of the European Commission (SYNGENE), iMED grant of the Helmholtz Society, DKFZ Postdoctoral Fellowship.

  • Input: -

  • Output: -

  • Contact: Florian Heigwer f.heigwer@dkfz.de, Michael Boutros m.boutros@dkfz.de

  • Collection: -

  • Maturity: -

Publications

  • CRISPR library designer (CLD): software for multispecies design of single guide RNA libraries.
  • Heigwer F, Zhan T, Breinig M, Winter J, Brügemann D, Leible S, Boutros M. CRISPR library designer (CLD): software for multispecies design of single guide RNA libraries. Genome Biol. 2016 Mar 24;17:55. doi: 10.1186/s13059-016-0915-2. PMID: 27013184; PMCID: PMC4807595.
  • https://doi.org/10.1186/s13059-016-0915-2
  • PMID: 27013184
  • PMC: PMC4807595

Download and documentation

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