CRISPOR

CRISPOR is a web-based tool to edit and experiment with CRISPR–Cas9 to assess off- and on-target scoring algorithms and integration into the guide RNA.

Topic

RNA;Genomics;Genetics

Detail

  • Operation: Target-Decoy

  • Software interface: Web user interface

  • Language: -

  • License: CC-BY-4.0

  • Cost: Free

  • Version name: -

  • Credit: The International Phenotyping Consortium at MRC Harwell, the Medical Research Council, National Institutes of Health, the California Institute of Regenerative Medicine, the Agence Nationale pour la Recherche, the Fondation pour la Recherche Médicale.

  • Input: -

  • Output: -

  • Contact: crispor@tefor.net, Maximilian Haeussler max@soe.ucsc.edu

  • Collection: -

  • Maturity: -

Publications

  • CRISPOR: intuitive guide selection for CRISPR/Cas9 genome editing experiments and screens.
  • Concordet JP, Haeussler M. CRISPOR: intuitive guide selection for CRISPR/Cas9 genome editing experiments and screens. Nucleic Acids Res. 2018 Jul 2;46(W1):W242-W245. doi: 10.1093/nar/gky354. PMID: 29762716; PMCID: PMC6030908.
  • https://doi.org/10.1093/nar/gky354
  • PMID: 29762716
  • PMC: PMC6030908
  • Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR.
  • Haeussler M, et al. Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR. Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR. 2016; 17:148. doi: 10.1186/s13059-016-1012-2
  • https://doi.org/10.1186/s13059-016-1012-2
  • PMID: 27380939
  • PMC: PMC4934014

Download and documentation

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