ChimeraScan

ChimeraScan is an open-source software package designed for the discovery of chimeric transcription between two independent transcripts in high-throughput transcriptome sequencing data. It enables de novo gene fusion discovery that could reveal candidates with therapeutic significance in cancer.

Topic

Gene transcripts;RNA-Seq;Oncology;Transcriptomics

Detail

  • Operation: Chimera detection;RNA-Seq analysis

  • Software interface: Command-line user interface

  • Language: Python

  • License: GNU General Public License, version 3

  • Cost: Free

  • Version name: 0.4.5a

  • Credit: Department of Defense Breast Cancer Predoctoral Grant, Prostate Cancer Foundation Young Investigator Award, National Institutes of Health Pathway to Independence, National Institutes of Health, Department of Defense and Early Detection Research Network.

  • Input: -

  • Output: -

  • Contact: cmaher@dom.wustl.edu

  • Collection: -

  • Maturity: -

Publications

  • ChimeraScan: a tool for identifying chimeric transcription in sequencing data.
  • Iyer MK, et al. ChimeraScan: a tool for identifying chimeric transcription in sequencing data. ChimeraScan: a tool for identifying chimeric transcription in sequencing data. 2011; 27:2903-4. doi: 10.1093/bioinformatics/btr467
  • https://doi.org/10.1093/bioinformatics/btr467
  • PMID: 21840877
  • PMC: PMC3187648

Download and documentation

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