Combenefit

Combenefit is a user-friendly software tool that provides scientists and bioinformaticians with a simple, systematic way to visualize, analyze, and quantify the effects of drug combinations. It supports classical Synergy models, Loewe, Bliss, and HSA, and can process data from single experiments or batches of High Throughput Screens.

Topic

Pharmacology;Personalised medicine;Drug metabolism

Detail

  • Operation: Metabolic network modelling

  • Software interface: Graphical user interface

  • Language: MATLAB

  • License: The MIT licence

  • Cost: Free

  • Version name: 2.021

  • Credit: The Cancer Research UK.

  • Input: -

  • Output: -

  • Contact: Giovanni.DiVeroli@cruk.cam.ac.uk

  • Collection: -

  • Maturity: -

Publications

  • Combenefit: an interactive platform for the analysis and visualization of drug combinations.
  • Di Veroli GY, et al. Combenefit: an interactive platform for the analysis and visualization of drug combinations. Combenefit: an interactive platform for the analysis and visualization of drug combinations. 2016; 32:2866-8. doi: 10.1093/bioinformatics/btw230
  • https://doi.org/10.1093/bioinformatics/btw230
  • PMID: 27153664
  • PMC: PMC5018366

Download and documentation


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