DCN
"DCN" is an open-source software package for analyzing longitudinal electronic medical records (EMR) to determine temporal correlations between various disease states. This tool leverages vast amounts of patient data to identify potential relationships between chronic diseases, formulating novel research hypotheses to explore these associations further.
Key Features and Functionalities:
- Temporal Correlation Analysis: DCN specializes in identifying temporal correlations between disease states by analyzing patient EMR data. This feature is crucial for understanding how various diseases may relate to each other in a chronological context.
- Large-scale Data Handling: The software has been applied to a substantial longitudinal dataset from Loyola University Chicago Medical Center, encompassing 654,084 initial diagnoses of 51 conditions across 175,539 patients, demonstrating DCN's ability to handle and analyze large-scale medical datasets effectively.
- Literature-supported Findings: Over 90% of the disease correlations identified by DCN have been supported by a literature review, indicating high accuracy and reliability in the tool's analysis and predictions.
- Potential for Novel Hypotheses: By screening EMR data for correlations between chronic diseases, DCN provides a valuable resource for healthcare researchers to uncover new relationships that have not been documented. This data can generate novel research hypotheses, potentially leading to new insights into disease mechanisms and interactions.
Topic
Pathology;Public health and epidemiology;Cardiology;Literature and language
Detail
Operation: Regression analysis;Incident curve plotting;Standardisation and normalisation
Software interface: Command-line interface
Language: R
License: Not stated
Cost: Free of charge
Version name: v1.2
Credit: -
Input: -
Output: -
Contact: Qunfeng Dong qdong@luc.edu
Collection: -
Maturity: -
Publications
- Disease correlation network: a computational package for identifying temporal correlations between disease states from Large-Scale longitudinal medical records.
- Lin H, et al. Disease correlation network: a computational package for identifying temporal correlations between disease states from Large-Scale longitudinal medical records. Disease correlation network: a computational package for identifying temporal correlations between disease states from Large-Scale longitudinal medical records. 2019; 2:353-359. doi: 10.1093/jamiaopen/ooz031
- https://doi.org/10.1093/JAMIAOPEN/OOZ031
- PMID: 31984368
- PMC: PMC6952009
Download and documentation
Documentation: https://github.com/qunfengdong/DCN/blob/master/README.md
Home page: https://github.com/qunfengdong/DCN
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