DChIPRep

DChIPRep is an R package to facilitate the genome-wide study of epigenetic states through the integrative analysis of histone modification ChIP-seq data. It provides an accessible analytical framework for comparing enrichment profiles of histone modifications around various genomic elements, such as transcription start sites (TSS). A key feature of DChIPRep is its ability to incorporate biological replicate information and chromatin Input data, enabling a more rigorous and reliable assessment of differential enrichment. This tool aims to simplify complex epigenetic analyses, making it a valuable asset for researchers in the field. Users can contact the developers directly via the provided email for further inquiries or support.

Topic

ChIP-seq

Detail

  • Operation: Nucleic acid feature detection

  • Software interface: Command-line user interface,Library

  • Language: R

  • License: The MIT License

  • Cost: Free

  • Version name: 1.4.0

  • Credit: Boerhinger Ingelheim Fonds, the Deutsche Forschungsgemeinschaft.

  • Input: -

  • Output: -

  • Contact: Bernd Klaus bernd.klaus@embl.de

  • Collection: -

  • Maturity: Stable

Publications

  • DChIPRep, an R/Bioconductor package for differential enrichment analysis in chromatin studies.
  • Chabbert CD, et al. DChIPRep, an R/Bioconductor package for differential enrichment analysis in chromatin studies. DChIPRep, an R/Bioconductor package for differential enrichment analysis in chromatin studies. 2016; 4:e1981. doi: 10.7717/peerj.1981
  • https://doi.org/10.7717/peerj.1981
  • PMID: 27168989
  • PMC: PMC4860309

Download and documentation


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