DisGeNET

DisGeNET is a powerful software tool that is designed to facilitate the interpretation and analysis of gene-disease networks. It is a Cytoscape plugin that provides users with easy and user-friendly access to a new gene-disease database. This database is created by integrating data from multiple public sources, which ensures that users have access to a comprehensive and up-to-date resource.

One of the key features of DisGeNET is its ability to perform queries that are restricted to specific criteria. Users can query the database based on the original data source, association type, disease class, or specific gene(s)/disease(s). This allows users to quickly and easily find the information they need without having to sift through irrelevant data.

The gene-disease associations are represented in bipartite graphs, which can be viewed in gene-centric or disease-centric ways. This flexibility allows users to explore the data in a way that is most useful to them. DisGeNET also offers built-in functions that assist users in the interpretation and exploration of the genetic basis of human diseases. These functions make it easier for users to understand the underlying genetic mechanisms of diseases, and to identify potential treatment targets.

DisGeNET permits multi colouring of nodes (genes/diseases) according to a standard disease classification for expedient visualization. This feature makes it easy for users to quickly identify key genes and diseases related to a specific condition or disease class.