DrGaP

DrGaP is a software tool to determine driver genes and their pathways in cancer sequencing data sets. The DrGaP algorithm uses a heuristics strategy for the estimation of the chi-square distribution of the likelihood ratio test (LRT).

Topic

Sequencing;Oncology;Immunoproteins, genes and antigens

Detail

  • Operation: Pathway or network analysis

  • Software interface: Library

  • Language: R

  • License: GNU General Public License v3

  • Cost: Free

  • Version name: 0.1.0

  • Credit: National Institutes of Health, Advancing a Healthier Wisconsin Fund, National Natural Science Foundation of China.

  • Input: -

  • Output: -

  • Contact: Yan Lu ylu@mcw.edu, Pengyuan Liu pliu@mcw.edu

  • Collection: -

  • Maturity: Emerging

Publications

  • DrGaP: a powerful tool for identifying driver genes and pathways in cancer sequencing studies.
  • Hua X, Xu H, Yang Y, Zhu J, Liu P, Lu Y. DrGaP: a powerful tool for identifying driver genes and pathways in cancer sequencing studies. Am J Hum Genet. 2013 Sep 5;93(3):439-51. doi: 10.1016/j.ajhg.2013.07.003. Epub 2013 Aug 15. PMID: 23954162; PMCID: PMC3769934.
  • https://doi.org/10.1016/j.ajhg.2013.07.003
  • PMID: 23954162
  • PMC: PMC3769934

Download and documentation

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