EMMAX

EMMAX (Efficient Mixed-Model Association eXpedited) is a tool for testing association mapping considering the sample structure in genome-wide association studies (GWAS). The EMMAX algorithm uses a variance component approach that can analyze GWAS datasets within hours.

Topic

GWAS study

Detail

  • Operation: Genetic mapping

  • Software interface: Command-line user interface

  • Language: C++;C

  • License: -

  • Cost: Free

  • Version name: beta

  • Credit: National Science Foundation (NSF), National Institutes of Health (NIH), Microsoft Research, Samsung Scholarship, National Human Genome Research Institute, National Institute for Mental Health, GlaxoSmithKline, the University of California, Los Angeles, the National Toxicology Program and National Institute of Environmental Health Sciences; Perlegen Sciences.

  • Input: PED (PLINK)

  • Output: -

  • Contact: h3kang@umich.edu | sabatti@stanford.edu | eeskin@cs.ucla.edu

  • Collection: -

  • Maturity: -

Publications

  • Variance component model to account for sample structure in genome-wide association studies.
  • Kang HM, et al. Variance component model to account for sample structure in genome-wide association studies. Variance component model to account for sample structure in genome-wide association studies. 2010; 42:348-54. doi: 10.1038/ng.548
  • https://doi.org/10.1038/ng.548
  • PMID: 20208533
  • PMC: PMC3092069

Download and documentation

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