FSuite

FSuite is a pipeline that utilizes inbreeding information derived from human genomic data, which can make use of single nucleotide polymorphism chip or exome data. It includes a module to detect inbred individuals, estimate their inbreeding coefficient, and describe the proportion of different mating types in the population. Additionally, it allows the identification of shared regions of homozygosity between affected individuals (homozygosity mapping) that can be used to identify rare recessive mutations involved in monogenic or multifactorial diseases.