FunPart

FunPart is a computational tool designed to advance immunomodulation strategies crucial for various biomedical applications. Addressing the complexity and heterogeneity of the immune system's response to infections, FunPart aids in mapping functional immune cell states in mice against 12 different pathogens. It employs a single-cell analysis technique to differentiate immune cell types into distinct functional states while identifying gene modules that characterize these states.

Topic

Transcriptomics;Function analysis

Detail

  • Operation: Clustering;Gene regulatory network analysis

  • Software interface: Web user interface

  • Language: R

  • License: GNU General Public License v2

  • Cost: Free with restrictions

  • Version name: 1.0

  • Credit: Luxembourg National Research Fund, Spanish Ministry of Science and Innovation, MCI.

  • Input: Gene expression matrix [TSV]

  • Output: Clustered expression profiles, Annotated text

  • Contact: Antonio del Sol antonio.delsol@uni.lu

  • Collection: -

  • Maturity: Stable

Publications

  • A Catalogus Immune Muris of the mouse immune responses to diverse pathogens.
  • Barlier C, et al. A Catalogus Immune Muris of the mouse immune responses to diverse pathogens. A Catalogus Immune Muris of the mouse immune responses to diverse pathogens. 2021; 12:798. doi: 10.1038/s41419-021-04075-y
  • https://doi.org/10.1038/s41419-021-04075-y
  • PMID: 34404761
  • PMC: PMC8370971

Download and documentation


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