GLINT

GLINT is designed to help researchers quickly and easily analyze genome-wide DNA methylation data generated using the Illumina human methylation arrays. It provides an easy-to-use command-line interface that requires no programming knowledge, allowing users to execute an Epigenome-Wide Association Study (EWAS) analysis pipeline under different models while accounting for known confounders in methylation data. GLINT simplifies analyzing and interpreting epigenetic data, reducing the time and resources required to gain insights.

Topic

Methylated DNA immunoprecipitation;Sequence analysis;Epigenomics

Detail

  • Operation: Whole genome methylation analysis

  • Software interface: Command-line user interface

  • Language: Python

  • License: -

  • Cost: Free

  • Version name: 1.0.4

  • Credit: The Edmond J. Safra Center for Bioinformatics at Tel Aviv University, the Israel Science Foundation, the United States Israel Bintional Science Foundation, Len Blavatnik and the Blavatnik Research Foundation, the Colton Family Foundation, National Institutes of Health (NIH) career development award from the NHLBI.

  • Input: Text file (sites by samples matrix of methylation levels)

  • Output: -

  • Contact: elior.rahmani@gmail.com, ehalperin@cs.ucla.edu

  • Collection: -

  • Maturity: -

Publications

  • GLINT: a user-friendly toolset for the analysis of high-throughput DNA-methylation array data.
  • Rahmani E, et al. GLINT: a user-friendly toolset for the analysis of high-throughput DNA-methylation array data. GLINT: a user-friendly toolset for the analysis of high-throughput DNA-methylation array data. 2017; 33:1870-1872. doi: 10.1093/bioinformatics/btx059
  • https://doi.org/10.1093/bioinformatics/btx059
  • PMID: 28177067
  • PMC: PMC5870777

Download and documentation

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