GRcalculator

'GRcalculator' is a free and user-friendly web tool that was developed to facilitate analysis of dose-response data. The tool uses normalized growth rate (GR) inhibition to quantify drug response, which is robust to confounders such as varying numbers of cell divisions. The tool can be used to analyze dose-response data across diverse cell types and perturbagens (including drugs, biological ligands, RNAi, etc.) and provides access to data collected by the NIH LINCS Program and other public domain datasets. 'GRcalculator' generates publication-ready figures and provides a unified platform for investigators to analyze dose-response data. It also provides an R package called GRmetrics, specifically developed for offline analysis and visualization of GR metrics calculations within existing R analysis pipelines.