Gowinda

Gowinda is a software designed to test for enrichment of gene sets in genome-wide association (GWA) studies. It overcomes the limitations of gene set enrichment analysis that assumes independence and equal probability of sampling genes. Gowinda uses permutation tests to eliminate biases and maintain sufficient power to detect enrichment of gene sets.

Topic

Genomics;Population genetics;Sequencing;Population genomics

Detail

  • Operation: Gene-set enrichment analysis;Ontology comparison

  • Software interface: Ontology

  • Language: Java

  • License: Mozilla Public License 1.1

  • Cost: Free

  • Version name: 1.12

  • Credit: Austrian Science Fund (FWF).

  • Input: -

  • Output: -

  • Contact: 10.1093/bioinformatics/bts315 christian.schloetterer@vetmeduni.ac.at

  • Collection: -

  • Maturity: -

Publications

  • Gowinda: unbiased analysis of gene set enrichment for genome-wide association studies.
  • Kofler R and Schlötterer C. Gowinda: unbiased analysis of gene set enrichment for genome-wide association studies. Gowinda: unbiased analysis of gene set enrichment for genome-wide association studies. 2012; 28:2084-5. doi: 10.1093/bioinformatics/bts315
  • https://doi.org/10.1093/bioinformatics/bts315
  • PMID: 22635606
  • PMC: PMC3400962

Download and documentation

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