HELIQUEST

HELIQUEST is a server that calculates the physicochemical properties and amino acid composition of an alpha-helix and identifies protein segments with similar features. Additionally, it allows for manual or automatic mutation of helices to design analogues with defined features.

Topic

Genetic variation;Small molecules;Protein folding, stability and design;Genetics;Protein folds and structural domains

Detail

  • Operation: Nucleic acid property calculation;Protein property calculation

  • Software interface: Web user interface

  • Language: -

  • License: -

  • Cost: Free

  • Version name: -

  • Credit: Agence Nationale pour la Recherche; the CNRS (RISC).

  • Input: -

  • Output: -

  • Contact: heliquest@ipmc.cnrs.fr

  • Collection: -

  • Maturity: -

Publications

  • HELIQUEST: a web server to screen sequences with specific alpha-helical properties.
  • Gautier R, et al. HELIQUEST: a web server to screen sequences with specific alpha-helical properties. HELIQUEST: a web server to screen sequences with specific alpha-helical properties. 2008; 24:2101-2. doi: 10.1093/bioinformatics/btn392
  • https://doi.org/10.1093/bioinformatics/btn392
  • PMID: 18662927
  • PMC: -

Download and documentation

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