HIVprotI

HIVprotI is a web-based service to predict HIV protein inhibitors. The HIVprotI algorithm can predict the IC50/Percent inhibition of user-specified compounds, i.e., proteases, integrases, and reverse transcriptases. The HIVprotI algorithm uses a Support Vector Machine (SVM) based regression model with experimentally validated ChEMBL data.

Topic

Cheminformatics;Enzymes;Protein interactions

Detail

  • Operation: Protein interaction prediction

  • Software interface: Web user interface

  • Language: Javascript;PHP;Perl

  • License: GNU General Public License v3

  • Cost: Free

  • Version name: -

  • Credit: Bioinformatics Centre, Institute of Microbial Technology, Council of Scientific and Industrial Research, Sector 39A, Chandigarh, 160036 India

  • Input: -

  • Output: -

  • Contact: Manoj Kumar manojk@imtech.res.in

  • Collection: -

  • Maturity: -

Publications

  • HIVprotI: an integrated web based platform for prediction and design of HIV proteins inhibitors.
  • Qureshi A, Rajput A, Kaur G, Kumar M. HIVprotI: an integrated web based platform for prediction and design of HIV proteins inhibitors. J Cheminform. 2018 Mar 9;10(1):12. doi: 10.1186/s13321-018-0266-y. PMID: 29524011; PMCID: PMC5845081.
  • https://doi.org/10.1186/s13321-018-0266-y
  • PMID: 29524011
  • PMC: PMC5845081

Download and documentation

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