HTSanalyzeR

HTSanalyzeR is a software tool designed to analyze high-throughput screening data from RNAi or small molecule experiments on a genome-wide scale. It integrates over-representation analysis, gene set enrichment analysis, comparative gene set analysis, and sub-network identification. It is written in R and interfaces with commonly used pre-processing packages, presenting results in HTML pages and network plots.

Topic

Functional genomics;RNAi experiment;Molecular interactions, pathways and networks

Detail

  • Operation: Gene set testing;Gene-set enrichment analysis;Gene to pathway mapping

  • Software interface: Command-line user interface;Library

  • Language: R

  • License: Artistic-2.0

  • Cost: Free

  • Version name: 2.3.5

  • Credit: The University of Cambridge, Cancer Research UK, Hutchison Whampoa Limited, Fondation Philippe Wiener - Maurice Anspach.

  • Input: -

  • Output: -

  • Contact: xinwang2hms@gmail.com

  • Collection: -

  • Maturity: Mature

Publications

  • HTSanalyzeR: an R/Bioconductor package for integrated network analysis of high-throughput screens.
  • Wang X, et al. HTSanalyzeR: an R/Bioconductor package for integrated network analysis of high-throughput screens. HTSanalyzeR: an R/Bioconductor package for integrated network analysis of high-throughput screens. 2011; 27:879-80. doi: 10.1093/bioinformatics/btr028
  • https://doi.org/10.1093/bioinformatics/btr028
  • PMID: 21258062
  • PMC: PMC3051329

Download and documentation

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