INSPEcT-GUI

INSPEcT-GUI is an R-Shiny interface designed to facilitate the exploration of RNA species abundance and their responses to perturbations based on the kinetics rates of RNA synthesis, processing, and degradation. This tool enables researchers, even without specific training, to interactively visualize gene-level RNA dynamics, refine model fits of experimental data, test alternative regulatory models, and explore the impact of RNA kinetic rates on premature and mature RNA independently of data availability. INSPEcT-GUI is part of the R/Bioconductor package INSPEcT.

Topic

RNA-Seq;Gene expression;RNA;Mathematics

Detail

  • Operation: Modelling and simulation;Expression analysis;Data handling

  • Software interface: Command-line user interface,Library

  • Language: R

  • License: GNU General Public License, version 2

  • Cost: Free

  • Version name: 1.31.0

  • Credit: -

  • Input: -

  • Output: -

  • Contact: Stefano de Pretis ste.depo@gmail.com, Mattia Furlan Mattia.Furlan@iit.it

  • Collection: -

  • Maturity: Stable

Publications

  • INSPEcT-GUI Reveals the Impact of the Kinetic Rates of RNA Synthesis, Processing, and Degradation, on Premature and Mature RNA Species.
  • de Pretis S, et al. INSPEcT-GUI Reveals the Impact of the Kinetic Rates of RNA Synthesis, Processing, and Degradation, on Premature and Mature RNA Species. INSPEcT-GUI Reveals the Impact of the Kinetic Rates of RNA Synthesis, Processing, and Degradation, on Premature and Mature RNA Species. 2020; 11:759. doi: 10.3389/fgene.2020.00759
  • https://doi.org/10.3389/FGENE.2020.00759
  • PMID: 32765590
  • PMC: PMC7379887

Download and documentation


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