KMAD

KMAD is a software package specifically designed to construct multiple sequence alignments (MSAs) of so-called intrinsically disordered proteins (IDPs). IDPs differ from globular proteins by lacking tertiary structure and by having lower sequence conservation. The Authors provide both stand-alone and web server versions.

Topic

Phylogeny;Sequence analysis;Nucleic acid sites, features and motifs;Nucleic acid structure analysis;Sequence sites, features and motifs

Detail

  • Operation: Multiple sequence alignment

  • Software interface: Command-line user interface;web user interface

  • Language: C++

  • License: Free Software Foundation

  • Cost: Free

  • Version name: 1.15

  • Credit: -

  • Input: FASTA;plain protein sequences

  • Output: -

  • Contact: vriend@cmbi.ru.nl | j.lange@radboudumc.nl

  • Collection: -

  • Maturity: Stable

Publications

  • KMAD: knowledge-based multiple sequence alignment for intrinsically disordered proteins.
  • Lange J, et al. KMAD: knowledge-based multiple sequence alignment for intrinsically disordered proteins. KMAD: knowledge-based multiple sequence alignment for intrinsically disordered proteins. 2016; 32:932-6. doi: 10.1093/bioinformatics/btv663
  • https://doi.org/10.1093/bioinformatics/btv663
  • PMID: 26568635
  • PMC: -

Download and documentation

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