UNLABELLED: During mitosis, chromosomes are attached to the mitotic spindle via
large protein complexes called kinetochores. The motion of kinetochores
throughout mitosis is intricate and automated quantitative tracking of their
motion has already revealed many surprising facets of their behaviour. Here, we
present 'KiT' (Kinetochore Tracking)-an easy-to-use, open-source software package
for tracking kinetochores from live-cell fluorescent movies. KiT supports 2D, 3D
and multi-colour movies, quantification of fluorescence, integrated
deconvolution, parallel execution and multiple algorithms for particle
localization. AVAILABILITY AND IMPLEMENTATION: KiT is free, open-source software
implemented in MATLAB and runs on all MATLAB supported platforms. KiT can be
downloaded as a package from http://www.mechanochemistry.org/mcainsh/software.php
The source repository is available at https://bitbucket.org/jarmond/kit and under
continuing development. SUPPLEMENTARY INFORMATION: Supplementary data are
available at Bioinformatics online. CONTACT: jonathan.armond@warwick.ac.uk.

KiT: a MATLAB package for kinetochore tracking.

KiT (Kinetochore Tracking) is an open-source program for analyzing kinetochores in real-time fluorescent movies. KiT includes various features, such as 2D, 3D, and multi-color imaging, fluorescence quantification, deconvolution, parallel processing, and different algorithms for particle detection.

KiT

Topic

Detail

Publications

Download and documentation