KnowSeq
The 'KnowSeq' R package is a comprehensive and modular software tool for automating and integrating various bioinformatic tools. It facilitates complex gene expression analyses, offering a unified environment to identify gene signatures associated with specific diseases. 'KnowSeq' handles raw files from different sources and transcriptomic technologies, employing advanced algorithms for tasks such as gene selection in multiclass problems. The tool incorporates an intelligent classification system, allowing users to choose from well-known classification and feature selection methods. Additionally, it automatically generates detailed HTML reports of the analysis. Experimental cases involving bi-class breast cancer and multiclass lung cancer demonstrate the efficacy of KnowSeq in achieving high classification rates and extracting relevant biological knowledge.
Topic
RNA-Seq;Transcriptomics;Workflows;Molecular interactions, pathways and networks;Ontology and terminology
Detail
Operation: Data retrieval;Differential gene expression profiling;Pathway visualisation
Software interface: Library
Language: R
License: GNU General Public License, version 2
Cost: Free
Version name: 1.16.0
Credit: -
Input: -
Output: -
Contact: Daniel Castillo-Secilla cased@ugr.es
Collection: -
Maturity: Stable
Publications
- KnowSeq R-Bioc package: The automatic smart gene expression tool for retrieving relevant biological knowledge.
- Castillo-Secilla D, et al. KnowSeq R-Bioc package: The automatic smart gene expression tool for retrieving relevant biological knowledge. KnowSeq R-Bioc package: The automatic smart gene expression tool for retrieving relevant biological knowledge. 2021; 133:104387. doi: 10.1016/j.compbiomed.2021.104387
- https://doi.org/10.1016/J.COMPBIOMED.2021.104387
- PMID: 33872966
- PMC: -
Download and documentation
Source: https://bioconductor.org/src/contrib/KnowSeq_1.16.0.tar.gz
Documentation: https://bioconductor.org/manuals/KnowSeq/man/KnowSeq.pdf
Home page: https://bioconductor.org/packages/KnowSeq
Links: https://bioconductor.org/vignettes/KnowSeq/inst/doc/KnowSeq.html
Links: https://bioconductor.org/vignettes/KnowSeq/inst/doc/KnowSeq.R
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