MI-MAAP
MI-MAAP is a web-based tool for ranking ancestry informative markers (AIMs) within reference ancestral populations with maximum information content utilizing the 1000 Genomes Project, Human Genome Diversity Project, and other genomic resources. The MI-MAAP algorithm uses a novel allele frequency-based feature selection, Principal Component Analysis (PCA), Lancaster Estimator of Independence (LEI), Support Vector Machine (SVM), and Random Forest (RF) methods.
Topic
Mapping;Population genetics;Genotype and phenotype;DNA polymorphism;Genomics
Detail
Operation: Essential dynamics;Genotyping;Haplotype mapping;Principal component visualisation;Nucleic acid feature detection
Software interface: Web user interface
Language: -
License: Open access, some restrictions
Cost: Free
Version name: -
Credit: National Institutes of Health (NIH)
Input: -
Output: -
Contact: Siqi Chen chen2se@mail.uc.edu, Sudhir Ghandikota Sudhir.ghandikota@cchmc.org, Yadu Gautam yadu.gautam@cchmc.org, Tesfaye B. Mersha tesfaye.mersha@cchmc.org
Collection: -
Maturity: -
Publications
- MI-MAAP: marker informativeness for multi-ancestry admixed populations.
- Chen S, Ghandikota S, Gautam Y, Mersha TB (2020). MI-MAAP: marker informativeness for multi-ancestry admixed populations. BMC Bioinformatics 21(1): 131.
- https://doi.org/10.1186/s12859-020-3462-5
- PMID: 32245404
- PMC: PMC7119171
Download and documentation
Documentation: https://research.cchmc.org/mershalab/MI-MAAP/manual/
Home page: https://research.cchmc.org/mershalab/MI-MAAP/login/
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