MetaboSignal

The software tool "MetaboSignal" is an R package designed for merging metabolic and signaling pathways, as reported in the Kyoto Encyclopaedia of Genes and Genomes (KEGG). It employs a network-based approach to explore topological relationships between genes (signaling- or metabolic genes) and metabolites. This tool is a potent means to investigate the genetic landscape of metabolic phenotypes, offering a comprehensive approach to understanding the interplay between metabolic and signaling pathways.

Topic

Metabolomics;Molecular interactions, pathways and networks;Genetics

Detail

  • Operation: Metabolic network modelling

  • Software interface: Command-line user interface,Library

  • Language: R

  • License: The GNU General Public License v3.0

  • Cost: Free

  • Version name: 1.32.1

  • Credit: Medical Research Council Doctoral Training Centre PhD scholarship, Imperial College PhD-scholarship, La Caixa studentship, Portuguese Foundation for Science and Technology, the European Commission.

  • Input: -

  • Output: -

  • Contact: Andrea Rodriguez-Martinez andrea.rodriguez-martinez13@imperial.ac.uk, Rafael Ayala rafaelayalahernandez@gmail.com

  • Collection: -

  • Maturity: Stable

Publications

  • MetaboSignal: a network-based approach for topological analysis of metabotype regulation via metabolic and signaling pathways.
  • Rodriguez-Martinez A, et al. MetaboSignal: a network-based approach for topological analysis of metabotype regulation via metabolic and signaling pathways. MetaboSignal: a network-based approach for topological analysis of metabotype regulation via metabolic and signaling pathways. 2017; 33:773-775. doi: 10.1093/bioinformatics/btw697
  • https://doi.org/10.1093/bioinformatics/btw697
  • PMID: 28011775
  • PMC: PMC5408820

Download and documentation

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