MethylCoder

MethylCoder is a software program designed to generate per-base methylation data from a set of bisulfite-treated reads. It supports two short-read aligners, accounts for soft-masked alignments and overlapping paired-end reads, and outputs data in text, binary, and SAM formats for compatibility with common high-throughput sequencing tools. MethylCoder is flexible, fast, and requires only a python interpreter and a C compiler to run.

Topic

Genomics;Sequencing;Epigenetics;Epigenomics

Detail

  • Operation: Read mapping;Bisulfite mapping

  • Software interface: Workflow

  • Language: Python;C

  • License: BSD License

  • Cost: Free

  • Version name: -

  • Credit: National Institute of Health.

  • Input: -

  • Output: -

  • Contact: bpederse@gmail.com

  • Collection: -

  • Maturity: Legacy

Publications

  • MethylCoder: software pipeline for bisulfite-treated sequences.
  • Pedersen B, et al. MethylCoder: software pipeline for bisulfite-treated sequences. MethylCoder: software pipeline for bisulfite-treated sequences. 2011; 27:2435-6. doi: 10.1093/bioinformatics/btr394
  • https://doi.org/10.1093/bioinformatics/btr394
  • PMID: 21724594
  • PMC: PMC3157921

Download and documentation


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