Mfuzz

"Mfuzz" is an R package for the soft clustering of microarray data, a technique that addresses several limitations associated with hard clustering methods. Hard clustering requires each gene (or sample) to belong to one specific cluster, which can lead to issues such as sensitivity to noise and loss of information. Soft clustering, on the other hand, allows for a gene to be assigned to multiple clusters, providing a more nuanced analysis that captures the complexities and overlapping nature of gene expression data.

The Mfuzz package implements soft clustering tools tailored for the nuanced analysis of microarray data, offering advantages over traditional hard clustering by mitigating its drawbacks. To enhance user accessibility and interaction with Mfuzz, an additional package, Mfuzzgui, features a convenient TclTk-based graphical user interface. This interface facilitates easier manipulation and exploration of microarray data through soft clustering.

Topic

Gene expression;Experimental design and studies

Detail

  • Operation: Clustering;Visualisation

  • Software interface: Command-line user interface,Library

  • Language: R

  • License: GNU General Public License, version 2

  • Cost: Free

  • Version name: 2.62.0

  • Credit: The SFB 618 grant of the Deutsche Forschungsgemeinschaft.

  • Input: -

  • Output: -

  • Contact: Matthias Futschik m@thias.futschik@sysbiolab.eu

  • Collection: -

  • Maturity: Stable

Publications

  • Mfuzz: a software package for soft clustering of microarray data.
  • Kumar L and E Futschik M. Mfuzz: a software package for soft clustering of microarray data. Mfuzz: a software package for soft clustering of microarray data. 2007; 2:5-7. doi: 10.6026/97320630002005
  • https://doi.org/10.6026/97320630002005
  • PMID: 18084642
  • PMC: PMC2139991

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