MultiBaC

MultiBaC is an R package to address batch effects in multi-omic datasets, where data may be obtained in different batches, and omics type and batch are often confounded. It explicitly targets scenarios involving hidden batch effects that may introduce systematic biases during data acquisition. Existing methods typically fail to correct batch effects in such complex cases.
The MultiBaC package provides a tool for batch effect removal and includes various graphical outputs for model validation and assessment of batch effect correction.

Topic

Data acquisition;Laboratory techniques;Statistics and probability;Gene expression

Detail

  • Operation: Essential dynamics;Visualisation

  • Software interface: Library

  • Language: R

  • License: The GNU General Public License v3.0

  • Cost: Free

  • Version name: 1.12.0

  • Credit: The Generalitat Valenciana through PROMETEO grants program for excellence research groups, the Spanish MICINN, Universitat Politècnica de València.

  • Input: -

  • Output: -

  • Contact: Manuel Ugidos manuelugidos@gmail.com

  • Collection: -

  • Maturity: Stable

Publications

  • MultiBaC: an R package to remove batch effects in multi-omic experiments.
  • Ugidos M, et al. MultiBaC: an R package to remove batch effects in multi-omic experiments. MultiBaC: an R package to remove batch effects in multi-omic experiments. 2022; 38:2657-2658. doi: 10.1093/bioinformatics/btac132
  • https://doi.org/10.1093/BIOINFORMATICS/BTAC132
  • PMID: 35238331
  • PMC: PMC9048667

Download and documentation

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