NullSeq

NullSeq is a tool to simulate random DNA sequences using the maximum entropy principle. A user can specify GC content and soecific amino acisid usage.

Topic

Sequencing

Detail

  • Operation: Random sequence generation

  • Software interface: Command-line user interface

  • Language: Python

  • License: -

  • Cost: Free

  • Version name: -

  • Credit: National Institute of General Medical Science, the Northwestern University Presidential Fellowship, the National Science Foundation, David and Lucile Packard Foundation, the Camille Dreyfus Teacher Scholar Award.

  • Input: -

  • Output: -

  • Contact: Luís A. N. Amaral amaral@northwestern.edu

  • Collection: -

  • Maturity: -

Publications

  • NullSeq: A Tool for Generating Random Coding Sequences with Desired Amino Acid and GC Contents.
  • Liu SS, Hockenberry AJ, Lancichinetti A, Jewett MC, Amaral LA. NullSeq: A Tool for Generating Random Coding Sequences with Desired Amino Acid and GC Contents. PLoS Comput Biol. 2016 Nov 11;12(11):e1005184. doi: 10.1371/journal.pcbi.1005184. PMID: 27835644; PMCID: PMC5106001.
  • https://doi.org/10.1371/journal.pcbi.1005184
  • PMID: 27835644
  • PMC: PMC5106001

Download and documentation

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