ORegAnno

ORegAnno (The Open Regulatory Annotation) is a database of literature-curated regulatory regions, transcription factor binding sites, and regulatory mutations that have been submitted, indexed, and validated from users worldwide. It is designed to provide a dynamic collection of regulatory elements that can be easily accessed through MySQL, web services, and online. Submissions are immediately cross-referenced to several databases, including EnsEMBL, dbSNP, Entrez Gene, the NCBI Taxonomy database, and PubMed. The software is available under the Lesser GNU Public License (LGPL). ORegAnno is a community-based approach to gene regulation that aims to provide a comprehensive and up-to-date resource for researchers to study and understand gene regulation.

Topic

Transcription factors and regulatory sites;Genetic variation;Gene expression;Gene regulation;Database management

Detail

  • Operation: Transcription factor binding site prediction;Transcriptional regulatory element prediction

  • Software interface: Database portal

  • Language: SQL

  • License: -

  • Cost: Free

  • Version name: -

  • Credit: Genome Canada, Genome British Columbia and the BC Cancer Foundation, the Natural Sciences and Engineering Research Council (NSERC), the Michael Smith Foundation for Health Research (MSFHR), the Canadian Institutes of Health Research (CIHR).

  • Input: -

  • Output: -

  • Contact: sjones@bcgsc.ca

  • Collection: -

  • Maturity: -

Publications

  • ORegAnno: an open access database and curation system for literature-derived promoters, transcription factor binding sites and regulatory variation.
  • Montgomery SB, et al. ORegAnno: an open access database and curation system for literature-derived promoters, transcription factor binding sites and regulatory variation. ORegAnno: an open access database and curation system for literature-derived promoters, transcription factor binding sites and regulatory variation. 2006; 22:637-40. doi: 10.1093/bioinformatics/btk027
  • https://doi.org/10.1093/bioinformatics/btk027
  • PMID: 16397004
  • PMC: -

Download and documentation

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