OligoCalc

OligoCalc is a tool to calculate the melting temperature, concentration, molecular weight, absorbance at 260 nanometers, and physical properties of single- and double-stranded DNA and RNA molecules. OligoCalc algorithm recognizes 5’ and 3’ chemical modifications and predicts potential hairpin loops.

Topic

Nucleic acid structure analysis;Physics;Protein modifications;DNA;RNA

Detail

  • Operation: Protein molecular weight calculation;Protein property calculation;Nucleic acid thermodynamic property calculation

  • Software interface: Web user interface

  • Language: Javascript

  • License: -

  • Cost: Free

  • Version name: 3.27

  • Credit: Northwestern University, The Feinberg School of Medicine and the Robert H. Lurie Comprehensive Cancer Center of Northwestern University

  • Input: -

  • Output: -

  • Contact: wakibbe@northwestern.edu

  • Collection: -

  • Maturity: Mature

Publications

  • OligoCalc: an online oligonucleotide properties calculator.
  • Kibbe WA. OligoCalc: an online oligonucleotide properties calculator. OligoCalc: an online oligonucleotide properties calculator. 2007; 35:W43-6. doi: 10.1093/nar/gkm234
  • https://doi.org/10.1093/nar/gkm234
  • PMID: 17452344
  • PMC: PMC1933198

Download and documentation


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