OmicsON

"OmicsON" is an R library designed to facilitate the integration and analysis of omics data, specifically focusing on transcriptomics and metabolomics data sets. With the proliferation of biological data across various databases, there's a growing need for sophisticated data integration methods that consolidate this data and allow for meaningful analysis by applying theoretical methods. OmicsON addresses this need by leveraging biological knowledge and mathematical procedures for data analysis.

Key Features:

- Data Integration: OmicsON enables the integration of transcriptomic and metabolomic data, providing a holistic view of the biological processes by analyzing gene expression and metabolite concentrations.

- Functional Grouping and Statistical Analysis: The tool applies functional grouping based on biological knowledge from well-known databases like Reactome and String. This approach allows for creating subgroups within the transcriptomic and metabolomic data sets, facilitating targeted analysis.

- Advanced Statistical Procedures: OmicsON employs multivariate statistical procedures, including Canonical Correlation Analysis (CCA) and Partial Least Squares (PLS), to analyze the integrated data sets. These methods are beneficial for exploring the relationships and correlations between the two data types.

- Biological Interpretation: The integration and analysis methodology implemented in OmicsON significantly aids in assessing the relationship between gene expression and metabolite concentrations. This capability enhances the biological interpretation of the studied processes, offering insights into how these two layers of omics data interact and influence each other.