PANTHER Database and Tools

Protein classification to ease high-throughput analyses. Classification is by family and subfamily, molecular function, biological process, and pathway. Updated single-nucleotide polymorphisms (SNP) scoring tool.

Topic

Sequence sites, features and motifs, Gene and protein families, Pathology, Molecular interactions, pathways and networks, Genetic variation

Detail

  • Operation: Over-representation analysis, Haplotype mapping, Protein modelling (mutation)

  • Software interface: Web user interface

  • Language: -

  • License: -

  • Cost: -

  • Version name: 14.0

  • Credit: Mi H, Huang X, Muruganujan A, Tang H, Mills, Kang, Thomas PD

  • Input: -

  • Output: -

  • Contact: -

  • Collection: -

  • Maturity: -

Publications

  • Large-scale gene function analysis with the PANTHER classification system.
  • Mi H, et al. Large-scale gene function analysis with the PANTHER classification system. Large-scale gene function analysis with the PANTHER classification system. 2013; 8:1551-66. doi: 10.1038/nprot.2013.092
  • https://doi.org/10.1038/nprot.2013.092
  • PMID: 23868073
  • PMC: PMC6519453
  • Protocol Update for large-scale genome and gene function analysis with the PANTHER classification system (v.14.0).
  • Mi H, et al. Protocol Update for large-scale genome and gene function analysis with the PANTHER classification system (v.14.0). Protocol Update for large-scale genome and gene function analysis with the PANTHER classification system (v.14.0). 2019; 14:703-721. doi: 10.1038/s41596-019-0128-8
  • https://doi.org/10.1038/s41596-019-0128-8
  • PMID: 30804569
  • PMC: PMC6519457
  • The PANTHER database of protein families, subfamilies, functions and pathways.
  • Mi H, et al. The PANTHER database of protein families, subfamilies, functions and pathways. The PANTHER database of protein families, subfamilies, functions and pathways. 2005; 33:D284-8. doi: 10.1093/nar/gki078
  • https://doi.org/10.1093/nar/gki078
  • PMID: 15608197
  • PMC: PMC540032
  • PANTHER version 7: improved phylogenetic trees, orthologs and collaboration with the Gene Ontology Consortium.
  • Mi H, et al. PANTHER version 7: improved phylogenetic trees, orthologs and collaboration with the Gene Ontology Consortium. PANTHER version 7: improved phylogenetic trees, orthologs and collaboration with the Gene Ontology Consortium. 2010; 38:D204-10. doi: 10.1093/nar/gkp1019
  • https://doi.org/10.1093/nar/gkp1019
  • PMID: 20015972
  • PMC: PMC2808919
  • PANTHER version 10: expanded protein families and functions, and analysis tools.
  • Mi H, et al. PANTHER version 10: expanded protein families and functions, and analysis tools. PANTHER version 10: expanded protein families and functions, and analysis tools. 2016; 44:D336-42. doi: 10.1093/nar/gkv1194
  • https://doi.org/10.1093/nar/gkv1194
  • PMID: 26578592
  • PMC: PMC4702852
  • PANTHER version 11: expanded annotation data from Gene Ontology and Reactome pathways, and data analysis tool enhancements.
  • Mi H, et al. PANTHER version 11: expanded annotation data from Gene Ontology and Reactome pathways, and data analysis tool enhancements. PANTHER version 11: expanded annotation data from Gene Ontology and Reactome pathways, and data analysis tool enhancements. 2017; 45:D183-D189. doi: 10.1093/nar/gkw1138
  • https://doi.org/10.1093/nar/gkw1138
  • PMID: 27899595
  • PMC: PMC5210595

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