PHESANT

PHESANT (PHEnome Scan ANalysis Tool) is a software package that automates comprehensive phenome scans in the UK Biobank, a large-scale epidemiological cohort. Phenome scans involve testing the association of a specific trait with a wide range of phenotypes, which can be challenging due to the heterogeneity of the models required.

Key features of PHESANT include:

1. Ability to test the association of a specified trait with all continuous, integer, and categorical variables in UK Biobank or a selected subset.

2. A novel rule-based algorithm that determines the appropriate test for each trait, ensuring a consistent and automated analysis process.

3. Automatic generation of plots and summary tables to present the phenome scan results.

Topic

Phenomics;Genotype and phenotype;Sequence analysis;Data visualisation;Data acquisition

Detail

  • Operation: Sequence analysis;Genome visualisation

  • Software interface: Command-line user interface

  • Language: R,Java

  • License: MIT License

  • Cost: Free of charge with restrictions

  • Version name: v1.1

  • Credit: University of Bristol and UK Medical Research Council.

  • Input: -

  • Output: -

  • Contact: Louise AC Millard louise.millard@bristol.ac.uk

  • Collection: -

  • Maturity: Stable

Publications

  • Software Application Profile: PHESANT: a tool for performing automated phenome scans in UK Biobank.
  • Millard LAC, et al. Software Application Profile: PHESANT: a tool for performing automated phenome scans in UK Biobank. Software Application Profile: PHESANT: a tool for performing automated phenome scans in UK Biobank. 2018; 47:29-35. doi: 10.1093/ije/dyx204
  • https://doi.org/10.1093/ije/dyx204
  • PMID: 29040602
  • PMC: PMC5837456

Download and documentation

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