PRIMUS

PRIMUS is a pedigree reconstruction algorithm that reconstructs pedigrees using genome-wide identity by descent estimates from observed genetic data. It has been expanded to include mitochondrial and non-recombining Y chromosome haplotypes to eliminate inconsistent pedigree structures.

Topic

Genetics;Statistics and probability

Detail

  • Operation: Pathway or network prediction

  • Software interface: Command-line user interface

  • Language: Perl

  • License: -

  • Cost: Free

  • Version name: -

  • Credit: The National Science Foundation Graduate Research Fellowship, the National Human Genome Research Institute, National Institute of Health Heart, Lung, and Blood Institute for the UW Center for Mendelian Genomics, the National Institute on Minority Health and Health Disparities.

  • Input: PLINK

  • Output: -

  • Contact: primus2@uw.edu

  • Collection: -

  • Maturity: Stable

Publications

  • PRIMUS: improving pedigree reconstruction using mitochondrial and Y haplotypes.
  • Staples J, et al. PRIMUS: improving pedigree reconstruction using mitochondrial and Y haplotypes. PRIMUS: improving pedigree reconstruction using mitochondrial and Y haplotypes. 2016; 32:596-8. doi: 10.1093/bioinformatics/btv618
  • https://doi.org/10.1093/bioinformatics/btv618
  • PMID: 26515822
  • PMC: PMC5963362

Download and documentation

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