Pigengene

"Pigengene" is a software tool for the analysis of gene expression data related to hematological malignancies. The 'Pigengene' software tool introduces a novel network analysis approach to distinguish between different types of hematological malignancies, specifically myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). The method utilizes the expression of eigengenes to uncover biological differences between these diseases.

Topic

Gene expression;Molecular interactions, pathways and networks;Statistics and probability

Detail

  • Operation: Statistical inference

  • Software interface: Command-line user interface,Library

  • Language: R

  • License: GNU General Public License, version 2

  • Cost: Free

  • Version name: 1.28.0

  • Credit: The Terry Fox Research Institute, CIHR, Genome BC, the John Auston BC Cancer Foundation Clinical Investigator award, an internal grant from Texas State University.

  • Input: -

  • Output: -

  • Contact: Habil Zare zare@u.washington.edu

  • Collection: -

  • Maturity: Stable

Publications

  • Large-scale gene network analysis reveals the significance of extracellular matrix pathway and homeobox genes in acute myeloid leukemia: an introduction to the Pigengene package and its applications.
  • Foroushani A, et al. Large-scale gene network analysis reveals the significance of extracellular matrix pathway and homeobox genes in acute myeloid leukemia: an introduction to the Pigengene package and its applications. Large-scale gene network analysis reveals the significance of extracellular matrix pathway and homeobox genes in acute myeloid leukemia: an introduction to the Pigengene package and its applications. 2017; 10:16. doi: 10.1186/s12920-017-0253-6
  • https://doi.org/10.1186/s12920-017-0253-6
  • PMID: 28298217
  • PMC: PMC5353782

Download and documentation

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