Proteny

Proteny is a tool that detects synteny between diverged genomes by operating on the amino acid sequence level, clustering groups of exons disregarding order, assigning significance levels to the syntenic clusters, and providing novel ways to visualize results at different scales. It is insensitive to codon usage adaptations and handles diversity in genomic ordering between genomes. Proteny is able to identify a more consistent synteny with more true homologies in fewer clusters that contain more genes in comparison to other tools.