RCAS

RCAS (RNA Centric Annotation System) is an R package designed to streamline the process of creating gene-centric annotations and analyses for genomic regions of interest derived from various RNA-based omics technologies. The modular design of RCAS facilitates flexible usage and seamless integration with other bioinformatics workflows. This R/Bioconductor package also provides graphical user interfaces, including a Galaxy wrapper and a standalone web service, to enhance accessibility. The application of RCAS on published datasets demonstrates its ability to replicate existing findings and generate novel knowledge and hypotheses. The tool offers meta-gene profiles, gene-centric annotations, motif analysis, and gene-set analysis, providing valuable contextual information for understanding the functional aspects of diverse biological events involving RNAs.