RFMix

RFMix is a software tool to do discriminative modeling of local ancestry inference. The RFMix algorithm uses a random field conditionally parameterized by random forests trained on reference panels and is capable of automatically correcting errors in phasing.

Topic

Whole genome sequencing;Genetics;Human genetics;Population genetics

Detail

  • Operation: Ancestral reconstruction

  • Software interface: Command-line user interface

  • Language: C++

  • License: -

  • Cost: Free

  • Version name: 1.5.4

  • Credit: National Science Foundation (NSF) Graduate Research Fellowship, National Library of Medicine training grant, National Human Genome Research Institute grant, NSF Division of Mathematical Sciences grant.

  • Input: .txt

  • Output: .Viterbi.txt

  • Contact: Carlos D. Bustamante cdbustam@stanford.edu, Brian K. Maples bmaples@stanford.edu

  • Collection: -

  • Maturity: -

Publications

  • RFMix: a discriminative modeling approach for rapid and robust local-ancestry inference.
  • Maples BK, Gravel S, Kenny EE, Bustamante CD. RFMix: a discriminative modeling approach for rapid and robust local-ancestry inference. Am J Hum Genet. 2013 Aug 8;93(2):278-88. doi: 10.1016/j.ajhg.2013.06.020. Epub 2013 Aug 1. PMID: 23910464; PMCID: PMC3738819.
  • https://doi.org/10.1016/j.ajhg.2013.06.020
  • PMID: 23910464
  • PMC: PMC3738819

Download and documentation

< Back to DB search