RVFam

RVFam is an R software package designed to analyze rare and common sequencing variants in genome-wide association studies (GWAS) involving family data for continuous, binary, and survival traits. It offers single and multiple variant association tests and accounts for arbitrary family structures.

Topic

DNA polymorphism;Genetics;Sequencing

Detail

  • Operation: SNP detection;Genetic variation analysis

  • Software interface: Library

  • Language: R

  • License: GNU GENERAL PUBLIC LICENSE v2

  • Cost: Free

  • Version name: 1.1

  • Credit: The National Institutes of Health (NIH, National Heart, Lung, and Blood Institute (NHLBI)s Framingham Heart Study, the Robert Dawson Evans Endowment of the Department of Medicine at Boston University School of Medicine and Boston Medical Center.

  • Input: -

  • Output: -

  • Contact: mhchen@bu.edu

  • Collection: -

  • Maturity: -

Publications

  • RVFam: an R package for rare variant association analysis with family data.
  • Chen MH and Yang Q. RVFam: an R package for rare variant association analysis with family data. RVFam: an R package for rare variant association analysis with family data. 2016; 32:624-6. doi: 10.1093/bioinformatics/btv609
  • https://doi.org/10.1093/bioinformatics/btv609
  • PMID: 26508760
  • PMC: PMC4757926

Download and documentation

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