Rtpca

"Rtpca" is an R package that implements methods for predicting protein-protein interactions (PPIs) using thermal proteome profiling data obtained from a single condition or in a differential setting. The approach employed is termed thermal proximity coaggregation. The package provides user-friendly tools for exploring datasets to assess PPI predictive performance and seamlessly integrates with other R packages.

Topic

Proteomics;Protein interactions;Sequence analysis

Detail

  • Operation: Protein interaction prediction;Differential protein expression analysis;Expression analysis

  • Software interface: Library

  • Language: R

  • License: The GNU General Public License v3.0

  • Cost: Free

  • Version name: 1.12.0

  • Credit: The European Molecular Biology Laboratory (EMBL), the EMBL International PhD programme, the EMBL International Postdoc programme under Marie Skłodowska action found.

  • Input: -

  • Output: -

  • Contact: Nils Kurzawa nilskurzawa@gmail.com

  • Collection: -

  • Maturity: Stable

Publications

  • Rtpca: an R package for differential thermal proximity coaggregation analysis.
  • Kurzawa N, et al. Rtpca: an R package for differential thermal proximity coaggregation analysis. Rtpca: an R package for differential thermal proximity coaggregation analysis. 2021; 37:431-433. doi: 10.1093/bioinformatics/btaa682
  • https://doi.org/10.1093/BIOINFORMATICS/BTAA682
  • PMID: 32717044
  • PMC: PMC8058776

Download and documentation

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