SeSAW

SeSAW is a valuable software tool that enables researchers to identify functionally or evolutionarily conserved motifs in protein structures. It does so by locating sequence and structural similarities and quantifying them at the level of individual residues. By doing this, SeSAW allows researchers to better understand the relationships between different proteins and their functions.
One feature that makes SeSAW unique is its ability to present the results of its analysis in both 2D and 3D formats. The 2D format presents annotated alignments, while the 3D format shows structural superpositions. This makes it easier for researchers to visualize and compare the similarities and differences between the proteins they study.

Topic

Mapping

Detail

  • Operation: Functional mapping;Mapping;Alignment;Protein sequence analysis;Query

  • Software interface: Command-line user interface

  • Language: -

  • License: -

  • Cost: Free

  • Version name: -

  • Credit: The Japan Society for the Promotion of Science (JSPS).

  • Input: -

  • Output: -

  • Contact: Daron Standley standley@biken.osaka-u.ac.jp

  • Collection: -

  • Maturity: Legacy

Publications

  • SeSAW: balancing sequence and structural information in protein functional mapping.
  • Standley DM, et al. SeSAW: balancing sequence and structural information in protein functional mapping. SeSAW: balancing sequence and structural information in protein functional mapping. 2010; 26:1258-9. doi: 10.1093/bioinformatics/btq116
  • https://doi.org/10.1093/bioinformatics/btq116
  • PMID: 20299324
  • PMC: PMC2859130

Download and documentation


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