Snap2

Predicts effects of single amino acid substitutions (SNPs), using neural networks. Visualizes prediction scores as a heatmap.

Topic

Biology, Genetics, DNA polymorphism

Detail

  • Operation: Prediction and recognition

  • Software interface: Command-line interface, web user interface

  • Language: Perl

  • License: Other

  • Cost: Free

  • Version name: -

  • Credit: Hecht M, Bromberg Y, Rost B.

  • Input: -

  • Output: -

  • Contact: Hecht M hecht at rostlab.org

  • Collection: -

  • Maturity: -

Publications

  • News from the protein mutability landscape.
  • Hecht M, et al. News from the protein mutability landscape. News from the protein mutability landscape. 2013; 425:3937-48. doi: 10.1016/j.jmb.2013.07.028
  • https://doi.org/10.1016/j.jmb.2013.07.028
  • PMID: 23896297
  • PMC: -
  • SNAP: predict effect of non-synonymous polymorphisms on function.
  • Bromberg Y and Rost B. SNAP: predict effect of non-synonymous polymorphisms on function. SNAP: predict effect of non-synonymous polymorphisms on function. 2007; 35:3823-35. doi: 10.1093/nar/gkm238
  • https://doi.org/10.1093/nar/gkm238
  • PMID: 17526529
  • PMC: PMC1920242
  • Better prediction of functional effects for sequence variants.
  • Hecht M, et al. Better prediction of functional effects for sequence variants. Better prediction of functional effects for sequence variants. 2015; 16 Suppl 8:S1. doi: 10.1186/1471-2164-16-S8-S1
  • https://doi.org/10.1186/1471-2164-16-S8-S1
  • PMID: 26110438
  • PMC: PMC4480835

Download and documentation

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