TPpred

TPpred is a tool to predict Eukaryotic organelle targeting peptides and cleavage sites. The TPpred3 algorithm uses Support Vector Machine (SVM) with a feature set from sequence motifs from a large set of mitochondrial and chloroplastic proteins. The TPpred3 organelle targeting peptides, classifies peptides into mitochondrial or chloroplastic and localizates cleavage sites.

Topic

Bioinformatics;Machine learning;Protein sites, features and motifs;Protein targeting and localisation;Small molecules

Detail

  • Operation: Protein subcellular localisation prediction;Protein cleavage site prediction;Protein feature detection

  • Software interface: Web user interface

  • Language: -

  • License: GNU General Public License v3.0

  • Cost: Free

  • Version name: 3.x

  • Credit: PRIN, Italian MIUR), European Union RTD Framework Program, Funding FARB-UNIBO.

  • Input: -

  • Output: -

  • Contact: Castrense Savojardo savojard@biocomp.unibo.it, gigi@biocomp.unibo.it

  • Collection: -

  • Maturity: -

Publications

  • TPpred2: improving the prediction of mitochondrial targeting peptide cleavage sites by exploiting sequence motifs.
  • Savojardo C, Martelli PL, Fariselli P, Casadio R. TPpred2: improving the prediction of mitochondrial targeting peptide cleavage sites by exploiting sequence motifs. Bioinformatics. 2014 Oct 15;30(20):2973-4. doi: 10.1093/bioinformatics/btu411. Epub 2014 Jun 27. PMID: 24974200.
  • https://doi.org/10.1093/bioinformatics/btu411
  • PMID: 24974200
  • PMC: -
  • TPpred3 detects and discriminates mitochondrial and chloroplastic targeting peptides in eukaryotic proteins.
  • Savojardo C, Martelli PL, Fariselli P, Casadio R. TPpred3 detects and discriminates mitochondrial and chloroplastic targeting peptides in eukaryotic proteins. Bioinformatics. 2015 Oct 15;31(20):3269-75. doi: 10.1093/bioinformatics/btv367. Epub 2015 Jun 16. PMID: 26079349.
  • https://doi.org/10.1093/bioinformatics/btv367
  • PMID: 26079349
  • PMC: -

Download and documentation

< Back to DB search