TargetSearch

The 'TargetSearch' software tool addresses challenges in metabolite profiling, specifically in the context of gas-chromatography hyphenated with mass spectrometry (GC-MS). With the increasing demand for large-scale experiments in systems-level biology, data pre-processing has become a bottleneck due to limitations in existing software. 'TargetSearch' introduces an open-source package that efficiently pre-processes even a large number of GC-MS samples within hours. It employs a novel iterative strategy to correct and update retention time indices for metabolite identification. 'TargetSearch' is designed to overcome limitations such as sample size constraints, systematic errors, and the need for extensive manual curation in existing software.