Trendy

Trendy is a software tool for characterizing gene expression patterns in RNA-seq data. The Trendy algorithm uses a regression model to identify segments by evaluating breakpoints in changes in expression to estimate the location and direction of changes in expression.

Topic

RNA-seq

Detail

  • Operation: Regression analysis

  • Software interface: Library

  • Language: R

  • License: GNU General Public License v3

  • Cost: Free

  • Version name: 1.20.0

  • Credit: The National Institutes of Health (NIH), the Charlotte Geyer Foundation, the Morgridge Institute for Research.

  • Input: -

  • Output: -

  • Contact: Rhonda Bacher rbacher@ufl.edu

  • Collection: -

  • Maturity: Stable

Publications

  • Trendy: segmented regression analysis of expression dynamics in high-throughput ordered profiling experiments
  • Bacher R, Leng N, Chu LF, Ni Z, Thomson JA, Kendziorski C, Stewart R. Trendy: segmented regression analysis of expression dynamics in high-throughput ordered profiling experiments. BMC Bioinformatics. 2018 Oct 16;19(1):380. doi: 10.1186/s12859-018-2405-x. PMID: 30326833; PMCID: PMC6192113.
  • https://doi.org/10.1186/s12859-018-2405-x
  • PMID: 30326833
  • PMC: PMC6192113

Download and documentation

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