Trinculo

Trinculo is an open-source program that allows users to perform multinomial logistic regression analyses to explore genetic relationships between multiple related phenotypes or disease subtypes. The program is designed to be easy to use and is compatible with standard genome-wide association study software.

Topic

Genetics;GWAS study;Pathology;Genotype and phenotype

Detail

  • Operation: Genetic variation analysis

  • Software interface: Command-line user interface

  • Language: R, Shell, Python

  • License: GNU General Public License v3

  • Cost: Free

  • Version name: 0.96

  • Credit: The Wellcome Trust, and by Christ Church, Oxford.

  • Input: -

  • Output: -

  • Contact: Luke Jostins lj4@well.ox.ac.uk

  • Collection: -

  • Maturity: -

Publications

  • Trinculo: Bayesian and frequentist multinomial logistic regression for genome-wide association studies of multi-category phenotypes.
  • Jostins L and McVean G. Trinculo: Bayesian and frequentist multinomial logistic regression for genome-wide association studies of multi-category phenotypes. Trinculo: Bayesian and frequentist multinomial logistic regression for genome-wide association studies of multi-category phenotypes. 2016; 32:1898-900. doi: 10.1093/bioinformatics/btw075
  • https://doi.org/10.1093/bioinformatics/btw075
  • PMID: 26873930
  • PMC: PMC4908321

Download and documentation

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