VCFtoTree

VCFtoTree is a software tool for constructing locus-specific phylogenies and sequence alignments. The VCFtoTree pipeline can download genome variation data from online public databases, such as 1000 Genomes Project, and includes tree building and sequence alignment algorithms.

Topic

Phylogenetics;Genomics;Sequence analysis;Population genetics

Detail

  • Operation: Phylogenetic tree generation

  • Software interface: Graphical user interface

  • Language: Python

  • License: -

  • Cost: Free

  • Version name: 3.0.0

  • Credit: UB Research Foundation through IMPACT grant program.

  • Input: fa.gz, vcf.gz

  • Output: FASTA, Newick

  • Contact: Duo Xu duoxu@buffalo.edu, Omer Gokcumen omergokc at buffalo.edu, Izzy Starr istarr at buffalo.edu

  • Collection: -

  • Maturity: -

Publications

  • VCFtoTree: a user-friendly tool to construct locus-specific alignments and phylogenies from thousands of anthropologically relevant genome sequences.
  • Xu D, Jaber Y, Pavlidis P, Gokcumen O. VCFtoTree: a user-friendly tool to construct locus-specific alignments and phylogenies from thousands of anthropologically relevant genome sequences. BMC Bioinformatics. 2017 Sep 26;18(1):426. doi: 10.1186/s12859-017-1844-0. PMID: 28950836; PMCID: PMC5615795.
  • https://doi.org/10.1186/s12859-017-1844-0
  • PMID: 28950836
  • PMC: PMC5615795

Download and documentation


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