cgHeliParm

cgHeliParm is a python program that performs conformational analysis on coarse-grained Martini-based double-strand DNA molecules. It provides helical parameters such as base, base pair, and base pair step parameters. It can be used to analyze coarse-grain Martini molecular dynamics trajectories without transforming them into atomistic models.

Topic

Simulation experiment;Computational chemistry;DNA;Nucleic acid structure analysis

Detail

  • Operation: Molecular dynamics

  • Software interface: Command-line user interface

  • Language: Python

  • License: -

  • Cost: Free

  • Version name: -

  • Credit: The Netherlands Scientific Organization (NWO ChemThem program)

  • Input: -

  • Output: -

  • Contact: Ignacio Faustino i.faustino@rug.nl

  • Collection: -

  • Maturity: -

Publications

  • cgHeliParm: analysis of dsDNA helical parameters for coarse-grained MARTINI molecular dynamics simulations
  • Faustino I, Marrink SJ. cgHeliParm: analysis of dsDNA helical parameters for coarse-grained MARTINI molecular dynamics simulations. Bioinformatics. 2017 Dec 1;33(23):3813-3815. doi: 10.1093/bioinformatics/btx444. PMID: 29036584.
  • https://doi.org/10.1093/bioinformatics/btx444
  • PMID: 29036584
  • PMC: -
  • 3DNA: a software package for the analysis, rebuilding and visualization of three‐dimensional nucleic acid structures
  • Lu XJ, Olson WK. 3DNA: a software package for the analysis, rebuilding and visualization of three-dimensional nucleic acid structures. Nucleic Acids Res. 2003 Sep 1;31(17):5108-21. doi: 10.1093/nar/gkg680. PMID: 12930962; PMCID: PMC212791.
  • https://doi.org/https://doi.org/10.1093/nar/gkg680
  • PMID: 12930962
  • PMC: PMC212791

Download and documentation


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