cgQTL

The software tool 'cgQTL' is a web tool that allows navigation between the map of bovine milk production QTL, potential candidate genes and their level of expression in mammary gland arrays and in GeneAtlas. The tool identifies candidate genes for QTL by hybridizing Affymetrix microarray with RNA derived from mammary gland of mice and combines data from two additional studies. A total of 249 differentially expressed probe sets common to the three experiments were identified and 212 genes were assigned to their bovine map positions through comparative mapping, thus forming a list of candidate genes for previously identified QTLs for milk production traits. The tool can be used to determine priority of candidate genes for QTN analysis based on differential expression in the target organ.

Topic

Genotype and phenotype

Detail

  • Operation: Data retrieval

  • Software interface: Database portal

  • Language: -

  • License: -

  • Cost: Free

  • Version name: -

  • Credit: Israel milk marketing board and the European Sixth Research and Technological Development Framework Programme, the University of California Davis Agricultural Experimental Station.

  • Input: -

  • Output: -

  • Contact: micha@agri.huji.ac.il

  • Collection: -

  • Maturity: -

Publications

  • Combining mouse mammary gland gene expression and comparative mapping for the identification of candidate genes for QTL of milk production traits in cattle.
  • Ron M, et al. Combining mouse mammary gland gene expression and comparative mapping for the identification of candidate genes for QTL of milk production traits in cattle. Combining mouse mammary gland gene expression and comparative mapping for the identification of candidate genes for QTL of milk production traits in cattle. 2007; 8:183. doi: 10.1186/1471-2164-8-183
  • https://doi.org/10.1186/1471-2164-8-183
  • PMID: 17584498
  • PMC: PMC1906769

Download and documentation

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